【】: Objective To investigate the clinicopathological features of sclerotic stromal tumor of the ovary and to provide reference for diagnosis and treatment. Methods The clinical data of 6 patients with sclerotic stromal tumor of ovary confirmed by clinicopathology admitted to Yunnan Cancer Hospital from August 2005 to September 2023 were retrospectively analyzed. Results Among the 6 patients, the age of onset in this study was 16-78 years old, and the age span was larger than that reported in the literature. There were even 2 cases of postmenopausal women. There was 1 patient with abnormal menstruation, 1 patient with abdominal pain, 3 patients with pelvic mass, and 1 patient with other signs. All 6 cases of sclerosed ovarian stromal tumor were single, and most of them were left side. In 6 cases, intraoperative freezing could only provide morphologic and pathological diagnosis, but could not determine benign and malignant. In 5 cases, laparotomy and 1 case, [1]minimally invasive surgery were performed. Conclusion Solid tumor with no distant metastasis and normal tumor markers should be considered in preoperative imaging. The possibility of sclerosed ovarian stromal tumor should be considered. Minimally invasive surgery can be selected for women with fertility requirements, and full preservation of fertility function can be considered, with a good prognosis.