Objective To study the effects of Kuanyu Shuqi prescription and whey protein on postoperative breast cancer patients.Methods Ninety patients with breast cancer admitted to the First Affiliated Hospital of Xi'an Jiaotong University were divided into the control group and the observation group according to the random number table method, with 45 cases in each group. Nutritional support was given after radical mastectomy. The nutrition support program was conventional nutrition + whey protein for the control group, and was conventional nutrition + whey protein+ Kuanyu Shuqi recipe for the observation group. Record the changes of nutritional status indicators, such as body mass index (BMI), mid-arm muscle circumference (MAMC), serum hemoglobin (Hb), albumin (ALB) and so on. Assess the emotional state of patients with the self-rating depression scale (SDS) and self-rating anxiety scale (SAS). Compare the differences in nutritional status, quality of life, and negative psychological emotions of patients between the two groups.Results After intervention, the BMI, MAMC, Hb, and ALB of patients in the observation group were (18.4±2.8) kg·m^-2, (28.7±4.5) cm, (40.5±4.2) g·L^-1, (46.4±4.1) g·L^-1, repsectively. The observation group showed greater improvement in nutritional status than the control group (P<0.05). The SAS score was (37.68±2.16) and the SDS score was (38.68±1.65) in the observation group, and was respectively (57.75±2.15) and (42.58±2.89) in the control group. The emotional state of patients was improved much greater in the observation group than in the control group (P<0.05). The quality of life score of the observation group was significantly higher than that of the control group (P<0.05).Conclusion Kuanyu Shuqi prescription combined with whey protein can improve the survival status of breast cancer patients after surgery.