CD19 CAR-T therapy for an elderly patient with relapsed/refractory mantle cell lymphoma and chronic kidney disease: a case report and literature review
Author:
Affiliation:
Chongqing University Cancer Hospital, Chongqing, 400030, China
Mantle cell lymphoma (MCL) is a special subtype of non Hodgkin's B-cell lymphoma, characterized by both invasiveness and inertness. This article reports a case of a patient with relapsed/refractory MCL complicated with chronic kidney disease (CKD). The patient achieved complete remission after receiving CD19-targeted chimeric antigen receptor T-cell (CAR-T) immunotherapy. Through clinical analysis of the case and systematic literature review, the study aims to provide evidence-based medical support for personalized comprehensive treatment strategies for relapsed/refractory MCL.